Role of bone marrow stromal cells in irradiation leukemogenesis.

@article{Greenberger1996RoleOB,
  title={Role of bone marrow stromal cells in irradiation leukemogenesis.},
  author={Joel S. Greenberger and Michael W. Epperly and Nadia Jahroudi and Kay L Pogue-Geile and Leanne Berry and James Bray and Kristin Goltry},
  journal={Acta haematologica},
  year={1996},
  volume={96 1},
  pages={
          1-15
        }
}
The role of bone marrow stromal cells of the hematopoietic microenvironment in ionizing-irradiation leukemogenesis is a focus of current investigation. Evidence from recent in vitro and in vivo experiments suggests that damage by slowly proliferating cells of the hematopoietic microenvironment contributes to the sustained survival of irradiation-damaged hematopoietic progenitor cells/stem cells and can contribute to the selection and proliferation of a malignant clone. The molecular mechanism… CONTINUE READING

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Donor cell leukemia: a review.

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