Role of bittergourd fruit juice in stz-induced diabetic state in vivo and in vitro.

@article{Sitasawad2000RoleOB,
  title={Role of bittergourd fruit juice in stz-induced diabetic state in vivo and in vitro.},
  author={Sandhya L. Sitasawad and Yogita Shewade and Ramesh Ramachandra Bhonde},
  journal={Journal of ethnopharmacology},
  year={2000},
  volume={73 1-2},
  pages={71-9}
}
The aqueous juice of bittergourd fruit (BF) (Momordica charantia L.) of the family Cucurbitaceae has been shown to possess hypoglycemic activity. However, the mechanism of its action is not known. Hence in vitro and in vivo experiments were carried out to study the role of BF juice on the diabetic status. The activity of BF juice was tested on STZ treated RIN cells and isolated islets in vitro. It was found that feeding with BF juice caused reduction in STZ-induced hyperglycemia in mice. It… CONTINUE READING

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