Role of bile acids, prostaglandins and COX inhibitors in chronic esophagitis in a mouse model.

Abstract

AIM To develop a new experimental model of esophagitis that serves a complementary tool to clinical investigation in an insight into the mechanism of the damage to the esophagus mucosa by aggressive factors, and role of COX inhibitors in this process. METHODS The study was conducted in 56 male mice. Animals were divided into seven groups: (1) perfused… (More)

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