Role of beta-adrenergic blockade in the therapy of patients with myocardial infarction.

@article{Braunwald1983RoleOB,
  title={Role of beta-adrenergic blockade in the therapy of patients with myocardial infarction.},
  author={Eugene Braunwald and J. F. Esteban Muller and Robert A. Kloner and Peter R. Maroko},
  journal={The American journal of medicine},
  year={1983},
  volume={74 1},
  pages={113-23}
}
Beta-adrenergic blockade appears to have beneficial effects on ischemic myocardium, both in experimental animals and in patients. There is substantial evidence that beta blockade, when induced promptly after coronary occlusion, is capable of limiting the size of experimentally produced infarcts. Although many mechanisms of action have been proposed, the bulk of available evidence suggests that beta blockade reduces the severity of myocardial ischemia by reducing myocardial oxygen demands… CONTINUE READING

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