Role of beer in the modulation of degenerative processes. In vivo and in vitro integrative studies of the DNA protective activity, survival increase, antiproliferative potential and modulation of genetic methylation status

@inproceedings{Amo2017RoleOB,
  title={Role of beer in the modulation of degenerative processes. In vivo and in vitro integrative studies of the DNA protective activity, survival increase, antiproliferative potential and modulation of genetic methylation status},
  author={M. Amo and Mar{\'i}a T{\'a}nia},
  year={2017}
}
The aim of the present study was to examine the nutraceutic potential of lyophilised blond Lager beer, as well as two of its bioactive components: xanthohumol and folic acid. Several toxicity, antitoxicity, genotoxicity, antigenotoxicity and longevity endpoints were checked in the SMART in vivo Drosophila system. Cytotoxicity in HL-60 promyelocytic and NIH3T3 mouse fibroblasts cells, proapototic DNA fragmentation, comet assay, macroautophagy ac-tivity and methylation status were tested in in… CONTINUE READING

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