Role of avian pathogenic Escherichia coli virulence factors in bacterial interaction with chicken heterophils and macrophages.

@article{Mellata2003RoleOA,
  title={Role of avian pathogenic Escherichia coli virulence factors in bacterial interaction with chicken heterophils and macrophages.},
  author={Melha Mellata and Maryvonne Dho-Moulin and Charles Martin Dozois and Roy Curtiss and Brigitte Lehoux and John Morris Fairbrother},
  journal={Infection and immunity},
  year={2003},
  volume={71 1},
  pages={494-503}
}
Avian pathogenic Escherichia coli (APEC) cause extraintestinal disease in avian species via respiratory tract infection. Virulence factors associated with APEC include type 1 and P fimbriae, curli, aerobactin, lipopolysaccharide (LPS), K1 capsular antigen, temperature-sensitive hemagglutinin (Tsh), and an uncharacterized pathogen-specific chromosomal region (the 0-min region). The role of these virulence factors in bacterial interaction with phagocytes was investigated by using mutants of three… CONTINUE READING
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