Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat.

Abstract

We explored the origin and participation of atrophic tubules in the progression of interstitial fibrosis using a new microembolic rat model of chronic renal failure in which foci of atrophic tubules with cuff-like basement membrane thickening developed at 4 weeks. Atrophic tubules, immunoreactive for vimentin and platelet-derived growth factor, were… (More)

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@article{Suzuki2001RoleOA, title={Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat.}, author={T Suzuki and Masashi Kimura and Masatake Asano and Yoshihide Fujigaki and Akira Hishida}, journal={The American journal of pathology}, year={2001}, volume={158 1}, pages={75-85} }