Role of atrial natriuretic peptide (ANP) in the regulation of insulin secretion and vitality of pancreatic ß cells

Abstract

Background The cardiac hormone atrial natriuretic peptide (ANP) increases intracellular cyclic GMP levels via activation of the guanylyl cyclase-A (GC-A) receptor and exerts important endocrine effects regulating arterial blood pressure and intravascular volume. Besides these wellknown effects, several studies suggest a role for ANP and its receptor in the… (More)
DOI: 10.1186/2050-6511-16-S1-A92

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