Role of atrial endothelial cells in the development of atrial fibrosis and fibrillation in response to pressure overload.

@article{Kume2017RoleOA,
  title={Role of atrial endothelial cells in the development of atrial fibrosis and fibrillation in response to pressure overload.},
  author={Osamu Kume and Yasushi Teshima and Ichitaro Abe and Yuki Ikebe and Takahiro Oniki and Hidekazu Kondo and Shotaro Saito and Akira Fukui and Kunio Yufu and Masahiro Miura and Tatsuo Shimada and Naohiko Takahashi},
  journal={Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology},
  year={2017},
  volume={27},
  pages={18-25}
}
BACKGROUND Monocyte chemoattractant protein-1 (MCP-1)-mediated inflammatory mechanisms have been shown to play a crucial role in atrial fibrosis induced by pressure overload. In the present study, we investigated whether left atrial endothelial cells would quickly respond structurally and functionally to pressure overload to trigger atrial fibrosis and… CONTINUE READING