Role of astroglia in estrogen regulation of synaptic plasticity and brain repair.

@article{GarciaSegura1999RoleOA,
  title={Role of astroglia in estrogen regulation of synaptic plasticity and brain repair.},
  author={Luis-Miguel Garcia-Segura and Frederick Naftolin and John B. Hutchison and I{\~n}igo Azcoitia and Julie A Chowen},
  journal={Journal of neurobiology},
  year={1999},
  volume={40 4},
  pages={574-84}
}
Astroglia are targets for estrogen and testosterone and are apparently involved in the action of sex steroids on the brain. Sex hormones induce changes in the expression of glial fibrillary acidic protein, the growth of astrocytic processes, and the degree of apposition of astroglial processes to neuronal membranes in the rat hypothalamus. These changes are linked to modifications in the number of synaptic inputs to hypothalamic neurons. These findings suggest that astrocytes may participate in… CONTINUE READING

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