Role of astrocytes in the clearance of excess extracellular potassium

@article{Walz2000RoleOA,
  title={Role of astrocytes in the clearance of excess extracellular potassium},
  author={Wolfgang Walz},
  journal={Neurochemistry International},
  year={2000},
  volume={36},
  pages={291-300}
}
  • W. Walz
  • Published 1 April 2000
  • Biology
  • Neurochemistry International
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The astrocyte biochemistry.
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Chloride/anion channels in glial cell membranes
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Dynamics of ion fluxes between neurons, astrocytes and the extracellular space during neurotransmission
TLDR
The predictions of the tri-compartment model based on mass-action kinetics equations are extended by assessing the selective contribution of the astroglial and neuronal Na/K ATPase, or volume of the extracellular space on potassium dynamics, and their implications for neuronal information processing in the healthy and diseased brain are discussed.
Sodium dynamics in neurons and astrocytes under epileptifom conditions
TLDR
The results show that large and long-lasting Na transients occur during synchronized activity of the endogenous circuitry and suggest that metabolic support of neurons during enhanced activity, provided by astrocytes, is necessary to maintain neuronal Na homeostasis.
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