Role of ascorbic acid in promoting follicle integrity and survival in intact mouse ovarian follicles in vitro.

@article{Murray2001RoleOA,
  title={Role of ascorbic acid in promoting follicle integrity and survival in intact mouse ovarian follicles in vitro.},
  author={Alison Murray and Michael D. Molinek and Sandra J Baker and F. N. Kojima and Michael Smith and Stephen G. Hillier and Norah Spears},
  journal={Reproduction},
  year={2001},
  volume={121 1},
  pages={89-96}
}
Ascorbic acid has three known functions: it is necessary for collagen synthesis, promotes steroidogenesis and acts as an antioxidant. Within the ovary, most studies have concentrated on the role of ascorbic acid in luteal formation and regression and little is known about the function of this vitamin in follicular growth and development. Follicular growth and development were investigated in this study using an individual follicle culture system that allows the growth of follicles from the late… CONTINUE READING