Role of apoptosis in biology and pathology: resistance to apoptosis in colon carcinogenesis.

@article{Payne1995RoleOA,
  title={Role of apoptosis in biology and pathology: resistance to apoptosis in colon carcinogenesis.},
  author={Claire Margaret Payne and Harris Bernstein and Carol L. Bernstein and Harinder S. Garewal},
  journal={Ultrastructural pathology},
  year={1995},
  volume={19 4},
  pages={221-48}
}
The overview of apoptosis presented here emphasizes cell deletion in the immune system, with particular reference to T- and B-lymphocyte development, and the in vivo and in vitro senescence of human neutrophils. Some biochemical criteria that are used to identify apoptotic cells are described. Pitfalls in using agarose gel electrophoresis as the sole method for the identification of apoptotic cells are discussed. There are multiple modes of cell death that can be identified at the morphologic… CONTINUE READING
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