Role of apoptosis in autoimmunity

@article{Lorenz2000RoleOA,
  title={Role of apoptosis in autoimmunity},
  author={H-M. Lorenz and Maria-E. Herrmann and Thomas H. Winkler and Udo S Gaipl and Joachim R. Kalden},
  journal={Apoptosis},
  year={2000},
  volume={5},
  pages={443-449}
}
Apoptosis is a physiological form of cell death required to ensure that the rate of cell division is balanced by the rate of cell death in multicellular organisms. Dysregulation of apoptosis is associated with the pathogenesis of a wide array of diseases: cancer, neurodegeneration, autoimmunity, heart disease and others. In this review we collect arguments supporting a hypothesis of a dysregulated apoptosis leading to development of autoimmunity like systemic lupus erythematosus (SLE). This… CONTINUE READING

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