Role of antiprogestational therapy for meningiomas.

  title={Role of antiprogestational therapy for meningiomas.},
  author={Steven M. Grunberg},
  journal={Human reproduction},
  volume={9 Suppl 1},
Epidemiological evidence, including the greater incidence of female patients, a positive association with pregnancy, and a positive association with breast cancer suggested a role for female sex hormones (and hormonal modulation) in regulating the growth of meningioma. The detection of hormone receptors on meningioma specimens provided a mechanism for this effect. However, unlike breast cancer, progesterone receptors (not oestrogen receptors) predominate in meningioma. Clinical trials with anti… CONTINUE READING
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