Role of anterior temporal cortex in auditory sentence comprehension: an fMRI study

  title={Role of anterior temporal cortex in auditory sentence comprehension: an fMRI study},
  author={Colin J. Humphries and Kimberley Willard and Bradley R. Buchsbaum and Gregory Hickok},
Recent neuropsychological and functional imaging evidence has suggested a role for anterior temporal cortex in sentence-level comprehension. We explored this hypothesis using event-related fMRI. Subjects were scanned while they listened to either a sequence of environmental sounds describing an event or a corresponding sentence matched as closely as possible in meaning. Both types of stimuli required subjects to integrate auditory information over time to derive a similar meaning, but differ in… 
Response of anterior temporal cortex to syntactic and prosodic manipulations during sentence processing
The results suggest a parcellation of anterior temporal cortex into 1) an STG region that is sensitive both to the presence of syntactic information and is modulated by prosodic manipulations (in nonsyntactic stimuli); and 2) a more inferior left STS/MTG area that is more selective for syntactic structure.
FMRI reveals brain regions mediating slow prosodic modulations in spoken sentences
Generally, brain responses to speech melody were stronger in right than left hemisphere sites, suggesting a particular role of right cortical areas in the processing of slow prosodic modulations.
The role of left inferior frontal and superior temporal cortex in sentence comprehension: localizing syntactic and semantic processes.
Comparisons of the two anomalous conditions revealed higher levels of activation for the syntactic over the semantic condition in the left basal ganglia and for the semantic over the syntactically incorrect conditions in the mid-portion of the superior temporal gyrus, bilaterally.
Neural substrates of phonemic perception.
It is shown that an area extending along the left middle and anterior superior temporal sulcus (STS) is more responsive to familiar consonant-vowel syllables during an auditory discrimination task than to comparably complex auditory patterns that cannot be associated with learned phonemic categories.
Listening to narrative speech after aphasic stroke: the role of the left anterior temporal lobe.
The presence of a Wernicke's area lesion was associated with both impaired sentence comprehension and a reduced physiological response to heard narratives in the intact anterior left STS when compared to aphasic patients without temporal lobe damage and normal controls.
Disentangling syntax and intelligibility in auditory language comprehension
The current fMRI study aims to disentangle the functional neuroanatomy of intelligibility and syntax in an orthogonal design and demonstrates that the mid‐to‐anterior STS activation is associated with increasing speech intelligibility, while the mid-to‐posterior STG/STS is more sensitive to syntactic information within the speech.
Canonical Sentence Processing and the Inferior Frontal Cortex: Is There a Connection?
Abstract The role of left inferior frontal cortex (LIFC) in canonical sentence comprehension is controversial. Many studies have found involvement of LIFC in sentence production or complex sentence
Hierarchical Processing for Speech in Human Auditory Cortex and Beyond
The clear and vocoded sentences used by Okada et al. (2010) provided two physically dissimilar presentations of intelligible speech that the authors could use to identify acoustically insensitive neural responses; spectrally rotated stimuli allowed the authors to look for response changes due to intelligibility, independent of reductions in spectral detail.
Identifying Individual Differences in the Neural Correlates of Language Processing Using fMRI
The aim of the current Ph.D. project was to develop an fMRI paradigm to assesses different language processes and modalities in a stimulus-driven manner, keeping non-linguistic task demands to a minimum, validating the suitability of the paradigm for localizing differentlanguage processes.


Functional MRI studies of auditory comprehension
It is concluded that the activation pattern evoked by the English sentences reflects auditory comprehension and is further supported by additional control studies that have shown a markedly different pattern of activation by pure tone frequency glides.
Auditory Language Comprehension: An Event-Related fMRI Study on the Processing of Syntactic and Lexical Information
The present data may be taken to suggest an involvement of the left frontal and bilateral temporal cortex when processing syntactic information during comprehension.
Human Brain Language Areas Identified by Functional Magnetic Resonance Imaging
Although partly in conflict with the classical model of language localization, FMRI findings are generally compatible with reported lesion data and provide additional support for ongoing efforts to refine and extend the classicalmodel.
Delineation of single‐word semantic comprehension deficits in aphasia, with anatomical correlation
This study confirms the existence of separable deficits in semantic comprehension and points conclusively to the left posterior temporal and inferior parietal region as being critical for semantic processing.
The Cortical Representation of Speech
In this study, we compare regional cerebral blood flow (rCBF) while French monolingual subjects listen to continuous speech in an unknown language, to lists of French words, or to meaningful and
A syntactic specialization for Broca's area.
Functional MRI is used to identify cortical areas specifically involved in syntactic processing in Broca's area and establish the existence of distinct modules for the authors' knowledge of language.
The neurology of syntax: Language use without Broca's area
  • Y. Grodzinsky
  • Biology, Psychology
    Behavioral and Brain Sciences
  • 2000
Five empirical arguments are presented: experiments in sentence comprehension, cross-linguistic considerations, grammaticality and plausibility judgments, real-time processing of complex sentences, and rehabilitation, which indicate that language is a distinct, modularly organized neurological entity.
Functional MR Imaging during Auditory Word Perception: A Single-Trial Presentation Paradigm
Functional magnetic resonance imaging (fMRI), while still in relatively early stages of its development, has become a widespread tool for addressing issues in the neurobiology of language and other
Voice-selective areas in human auditory cortex
It is shown, using functional magnetic resonance imaging in human volunteers, that voice-selective regions can be found bilaterally along the upper bank of the superior temporal sulcus (STS), and their existence sheds new light on the functional architecture of the human auditory cortex.