Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.

@article{Riaz2004RoleOA,
  title={Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.},
  author={Amjid Ali Riaz and Yusheng Wang and Ren{\'e} Schramm and Tohru Sato and Michael Dieter Menger and Bengt W. Jeppsson and Henrik Thorlacius},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2004},
  volume={18 7},
  pages={881-3}
}
The aims of the present study were to determine the effects and mechanisms of angiotensin II (Ang II) on leukocyte-endothelium interactions and the role of Ang II in a novel model of ischemia/reperfusion (I/R) in the mouse colon. Ang II dose-dependently increased leukocyte rolling and adhesion in colonic venules. Importantly, Ang II-induced leukocyte rolling was completely inhibited by immunoneutralization of P-selectin, and leukocyte adhesion was abolished in lymphocyte function antigen-1 (LFA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Similar Papers

Loading similar papers…