Role of alpha adrenoceptors in opossum internal anal sphincter.

  title={Role of alpha adrenoceptors in opossum internal anal sphincter.},
  author={Shigeru Yamato and Satish Rattan},
  journal={The Journal of clinical investigation},
  volume={86 2},
The purpose of the present investigation was to examine the role of alpha adrenoceptors in the internal anal sphincter (IAS). Studies wer performed on alpha-chloralose anesthetized opossums. Resting pressure in the IAS (IASP) was recorded using low compliant continuously perfused catheters. The effects of the alpha-1 adrenoceptor agonist phenylephrine and alpha-2 adrenoceptor agonist clonidine and their corresponding selective antagonists, prazosin and yohimbine, respectively, were examined on… CONTINUE READING


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