Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats

@article{L2004RoleOA,
  title={Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats},
  author={Anh Dzung L{\^e} and Stephen Harding and Walter Juzytsch and Douglas Funk and Yavin Shaham},
  journal={Psychopharmacology},
  year={2004},
  volume={179},
  pages={366-373}
}
Alpha-2 adrenoceptors are known to be involved in stress-induced reinstatement of heroin and cocaine seeking in laboratory animals. Here, we studied the involvement of these receptors in stress-induced reinstatement of alcohol seeking by using an agonist (lofexidine) and an antagonist (yohimbine) of these receptors, which inhibit and activate, respectively, noradrenaline transmission. We also tested the effect of lofexidine and yohimbine on alcohol self-administration. Lofexidine is used… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 129 CITATIONS

Role of cues and contexts on drug-seeking behaviour.

  • British journal of pharmacology
  • 2014
VIEW 3 EXCERPTS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2005
2019

CITATION STATISTICS

  • 28 Highly Influenced Citations

  • Averaged 7 Citations per year over the last 3 years

  • 45% Increase in citations per year in 2018 over 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 73 REFERENCES

Pathways to relapse: factors controlling the reinitiation of drug seeking after abstinence.

  • Nebraska Symposium on Motivation. Nebraska Symposium on Motivation
  • 2004
VIEW 2 EXCERPTS

Similar Papers

Loading similar papers…