Role of alloreactive KIR2DS1(+) NK cells in haploidentical hematopoietic stem cell transplantation.

Abstract

In allo-HSCT, donor-derived, "alloreactive" NK cells have been shown to play a crucial role in the treatment of acute leukemia, contributing to eradication of leukemic blasts (GvL effect) and to clearance of residual recipient DCs and T lymphocytes (thus, preventing GvHD and graft rejection, respectively). Such alloreactive NK cells do not express CD94… (More)
DOI: 10.1189/jlb.0311137

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@article{Marcenaro2011RoleOA, title={Role of alloreactive KIR2DS1(+) NK cells in haploidentical hematopoietic stem cell transplantation.}, author={Emanuela Marcenaro and Simona Carlomagno and Silvia Fabiana Pesce and Mariella Della Chiesa and Alessandro Moretta and Simona Sivori}, journal={Journal of leukocyte biology}, year={2011}, volume={90 4}, pages={661-7} }