Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development.

@article{Choi2003RoleOA,
  title={Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development.},
  author={Ji-Yeob Choi and Josef Abel and Thomas Neuhaus and Yon Ko and Volker Harth and Nobuyuki Hamajima and Kazuo Tajima and Keun-young Yoo and Sue Kyung Park and Dong-Young Noh and Wonshik Han and Kuk-jin Choe and Sei-hyun Ahn and S W Kim and Ari P Hirvonen and Daehee Kang},
  journal={Pharmacogenetics},
  year={2003},
  volume={13 2},
  pages={67-72}
}
OBJECTIVE We examined the potential association between alcohol consumption and genetic polymorphisms in the alcohol metabolizing enzymes, CYP2E1 and ALDH2, in individual susceptibility to breast cancer in a Korean study population. METHODS Three hundred and forty-six histologically confirmed breast cancer patients and 377 controls with no present or previous history of cancer were recruited from several teaching hospitals in Seoul during 1995-2001. The CYP2E1 RsaI polymorphism was determined… CONTINUE READING

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