Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong.

  title={Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong.},
  author={Y Li and X. Huang and Ignatius Tak-sun Yu and Tze wai Wong and Hua Qian},
  journal={Indoor air},
  volume={15 2},
UNLABELLED Severe acute respiratory syndrome (SARS) is primarily transmitted by bio-aerosol droplets or direct personal contacts. This paper presents a detailed study of environmental evidence of possible airborne transmission in a hospital ward during the largest nosocomial SARS outbreak in Hong Kong in March 2003. Retrospective on-site inspections and measurements of the ventilation design and air distribution system were carried out on July 17, 2003. Limited on-site measurements of bio… 

Figures from this paper

Role of fomites in SARS transmission during the largest hospital outbreak in Hong Kong

A detailed mechanism-based investigation that explored the role of fomite transmission in the well-known Ward 8A outbreak reveals that the SARS coronavirus was most possible to have spread via the combined long-range airborne and fmite routes, and that the fomites played a non-negligible role in the transmission.

Ventilation control for airborne transmission of human exhaled bio-aerosols in buildings.

This review updates current knowledge of the airborne transmission of pathogens and the improvement of ventilation efficiency concerning the infection prevention.

Evidence for probable aerosol transmission of SARS-CoV-2 in a poorly ventilated restaurant

An outbreak involving three non-associated families in Restaurant X in Guangzhou, China, and the possibility of aerosol transmission of SARS-CoV-2 is assessed, showing that the infection distribution is consistent with a spread pattern representative of exhaled virus-laden aerosols.

Indoor transmission dynamics of expired SARS-CoV-2 virus in a model African hospital ward

Cough and sneeze droplets’ interactions with indoor air of a typical hospital clinic were studied to investigate the effectiveness of existing guidelines/protocols being adopted in the control of the widespread coronavirus disease (COVID-19) transmission.

Infection Risk of Indoor Airborne Transmission of Diseases in Multiple Spaces

Abstract This study aims to predict the spatial distribution of infection risk of airborne transmission diseases in hospital anterooms and isolation rooms, using computational fluid dynamics (CFD)



Evidence of airborne transmission of the severe acute respiratory syndrome virus.

Airborne spread of the virus appears to explain this large community outbreak of SARS in Hong Kong, and future efforts at prevention and control must take into consideration the potential for airborne spread of this virus.

Possible SARS Coronavirus Transmission during Cardiopulmonary Resuscitation

This investigation investigated a possible cluster of SARS-CoV infections in healthcare workers who used contact and droplet precautions during attempted cardiopulmonary resuscitation of a SARS patient, and a systematic approach to the problem was outlined.

A major outbreak of severe acute respiratory syndrome in Hong Kong.

SARS is a serious respiratory illness that led to significant morbidity and mortality in this cohort of 138 cases of suspected SARS during a hospital outbreak in Hong Kong.

Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong

Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread, and transmission through fomites or small aerosols cannot be ruled out.

Risk of indoor airborne infection transmission estimated from carbon dioxide concentration.

There is likely to be an achievable critical rebreathed fraction of indoor air below which airborne propagation of common respiratory infections and influenza will not occur and this work derives a non-steady-state version of the Wells-Riley equation which is especially useful in poorly ventilated environments.

Spread and prevention of some common viral infections in community facilities and domestic homes

Examination of the dispersal, persistence and control of some common viruses in the domestic home and in community facilities finds growing evidence that person-to-person transmission via the hands and contaminated fomites plays a key role in the spread of viral infections.

Update: outbreak of severe acute respiratory syndrome--worldwide, 2003.

This report summarizes SARS cases among U.S. residents and surveillance and prevention activities in the United States.

The size distribution of droplets in the exhaled breath of healthy human subjects.

  • R. PapineniF. Rosenthal
  • Medicine, Environmental Science
    Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine
  • 1997
C coughing produced the largest droplet concentrations and nose breathing the least, although considerable intersubject variability was observed, and the existence of larger sized droplets in the exhaled breath was confirmed.

Guidelines for environmental infection control in health-care facilities. Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC).

  • L. SehulsterR. Chinn
  • Medicine
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports
  • 2003
This report reviews previous guidelines and strategies for preventing environment-associated infections in health-care facilities and offers recommendations, including evidence-based recommendations supported by studies and experienced opinions based upon infection-control and engineering practices.