Role of advanced glycation end products (AGEs) and their receptor (RAGE) in the pathogenesis of diabetic microangiopathy.

@article{Yamagishi2003RoleOA,
  title={Role of advanced glycation end products (AGEs) and their receptor (RAGE) in the pathogenesis of diabetic microangiopathy.},
  author={Sho-ichi Yamagishi and Masayoshi Takeuchi and Yosuke Inagaki and Kazuo Nakamura and Tsutomu Imaizumi},
  journal={International journal of clinical pharmacology research},
  year={2003},
  volume={23 4},
  pages={129-34}
}
Diabetic vascular complication is a leading cause of acquired blindness, end-stage renal failure, a variety of neuropathies and accelerated atherosclerosis, which could account for disabilities and high mortality rates in patients with diabetes. Chronic hyperglycemia is essentially involved in the pathogenesis of diabetic micro- and macrovascular complications via various metabolic derangements. In this review, we discuss the molecular mechanisms of diabetic retinopathy and nephropathy… CONTINUE READING

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Advanced Glycation Endproducts Dissertation

ZUR ERLANGUNG, DES AKADEMISCHEN, +3 authors Marie Curie
2007
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