Role of advanced glycation end product receptors in the pathogenesis of diabetic retinopathy.

@article{AlMesallamy2011RoleOA,
  title={Role of advanced glycation end product receptors in the pathogenesis of diabetic retinopathy.},
  author={Hala O Al-Mesallamy and Lamiaa N A Hammad and Tarek A El-Mamoun and Basma M Khalil},
  journal={Journal of diabetes and its complications},
  year={2011},
  volume={25 3},
  pages={
          168-74
        }
}
PROBLEM Advanced glycation end products (AGEs) and the interaction with their receptors (RAGE) play an important role in the pathogenesis of diabetic retinopathy (DR). Our study investigated whether serum soluble (s) RAGE (sRAGE) could serve as a prognostic tool for identifying the susceptibility to DR. Moreover, we examined the association between soluble forms of vascular cell adhesion molecules (sVCAM-1), nitric oxide (NO) and sRAGE levels in serum and the severity of DR. METHODS… CONTINUE READING
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