Role of adiponectin in the development of high fat diet-induced metabolic abnormalities in mice.

@article{Hecker2011RoleOA,
  title={Role of adiponectin in the development of high fat diet-induced metabolic abnormalities in mice.},
  author={Peter Ammon Hecker and Karen M. O'Shea and Tatiana de Fatima Galvao and Bethany Hope Brown and William Chad Stanley},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2011},
  volume={43 2},
  pages={
          100-5
        }
}
The adipokine adiponectin is decreased in severe obesity and is inversely associated with adipose mass. Adiponectin is associated with insulin sensitivity and cardioprotection. Obesity frequently results in the development of a "cardiometabolic syndrome" characterized by increased circulating insulin and leptin, and cardiac hypertrophy and dysfunction. This study examined if adiponectin-deficiency affects the development of metabolic and cardiac abnormalities in response to modest obesity. Mice… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets.

  • American journal of physiology. Endocrinology and metabolism
  • 2012
VIEW 6 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Sexual dimorphism in obesity-mediated left ventricular hypertrophy.

  • American journal of physiology. Heart and circulatory physiology
  • 2013
VIEW 1 EXCERPT
CITES BACKGROUND