Role of adipocytokines in hepatic fibrosis.

  title={Role of adipocytokines in hepatic fibrosis.},
  author={Cristiana Bertolani and Fabio Marra},
  journal={Current pharmaceutical design},
  volume={16 17},
Hepatic fibrosis is a dynamic process whereby the liver responds to conditions of persistent damage. This leads to deposition of fibrillar extracellular matrix, altered hepatocyte regeneration, deranged microvascular architecture and cirrhosis. Accumulating data demonstrate that obesity and insulin resistance are associated with a more severe and faster progression of the fibrogenic process indifferent chronic liver diseases, and attention has focused on possible links between the adipose… CONTINUE READING


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