Role of adherence in interleukin-8 induction in Helicobacter pylori-associated gastritis.

@article{Rieder1997RoleOA,
  title={Role of adherence in interleukin-8 induction in Helicobacter pylori-associated gastritis.},
  author={Gabriele Rieder and Rudolf A. Hatz and Anthony Patrick Moran and Alfred Walz and M. J. K. Stolte and Georg A Enders},
  journal={Infection and immunity},
  year={1997},
  volume={65 9},
  pages={
          3622-30
        }
}
Active Helicobacter pylori-associated gastritis is characterized by a dense mucosal infiltration with granulocytes. Since H. pylori is noninvasive, secondary signals must induce the accumulation of granulocytes. Interleukin-8 (IL-8) has been shown to play a key role in this event. Using competitive reverse transcriptase-PCR on mRNA from gastric biopsies, we could show a clear correlation between the amount of IL-8 transcripts and the activity of H. pylori gastritis. Due to the inability of the… CONTINUE READING

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