Role of active oxygen species in diethyldithiocarbamate-induced gastric ulcer in the rat


Diethyldithiocarbamate, an inhibitor of Cu,Zn-superoxide dismutase, was recently found to be ulcerogenic in the rat stomach, and active oxygen species were found to be responsible for its ulcerogenicity. To clarify which active oxygen species play a role in ulcerogenesis, the effects of various scavengers and iron-chelators were studied. As superoxide… (More)
DOI: 10.1007/BF01951766


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