Role of acrocentric cen-pter satellite DNA in Robertsonian translocation and chromosomal non-disjunction.

@article{Choo1990RoleOA,
  title={Role of acrocentric cen-pter satellite DNA in Robertsonian translocation and chromosomal non-disjunction.},
  author={K. H. Choo},
  journal={Molecular biology & medicine},
  year={1990},
  volume={7 5},
  pages={437-49}
}
  • K. H. Choo
  • Published 1990 in Molecular biology & medicine
The centromeres and short arms of the human acrocentric chromosomes have in common several families of tandemly repeated DNA. Recent analyses have revealed that, within some of these families, clearly distinct subfamilies have evolved that are unique to one or a subset of the different acrocentric chromosomes. The existence and maintenance of subfamilies common to different chromosomes entail a process of regular exchange between the non-homologous chromosomes. This process is suggested for the… CONTINUE READING

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