Role of acetaldehyde in tobacco smoke addiction

@article{Talhout2007RoleOA,
  title={Role of acetaldehyde in tobacco smoke addiction},
  author={R. Talhout and A. Opperhuizen and J. V. Amsterdam},
  journal={European Neuropsychopharmacology},
  year={2007},
  volume={17},
  pages={627-636}
}
  • R. Talhout, A. Opperhuizen, J. V. Amsterdam
  • Published 2007
  • Medicine, Psychology
  • European Neuropsychopharmacology
  • This review evaluates the presumed contribution of acetaldehyde to tobacco smoke addiction. In rodents, acetaldehyde induces reinforcing effects, and acts in concert with nicotine. Harman and salsolinol, condensation products of acetaldehyde and biogenic amines, may be responsible for the observed reinforcing effect of acetaldehyde. Harman and salsolinol inhibit monoamine oxidase (MAO), and some MAO-inhibitors are known to increase nicotine self-administration and maintain behavioural… CONTINUE READING
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    References

    SHOWING 1-10 OF 105 REFERENCES
    Monoamine oxidases and tobacco smoking.
    • 130
    • PDF
    Acetaldehyde and its condensation products as markers in alcoholism.
    • M. Collins
    • Chemistry, Medicine
    • Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism
    • 1988
    • 36
    Nicotine and nonnicotine factors in cigarette addiction
    • J. Rose
    • Medicine
    • Psychopharmacology
    • 2005
    • 294
    Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms.
    • 64
    Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats
    • 141
    • PDF
    Monoamine oxidase and tobacco dependence.
    • 122
    Is ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol.
    • 55
    Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors.
    • 206