Role of a pre-existing neuropathy on the course of bortezomib-induced peripheral neurotoxicity.

@article{Lanzani2008RoleOA,
  title={Role of a pre-existing neuropathy on the course of bortezomib-induced peripheral neurotoxicity.},
  author={Francesca Lanzani and Laura Mattavelli and Barbara Frigeni and Fausto Rossini and Sara Cammarota and Daniela Petr{\`o} and Stefano Jann and Guido Cavaletti},
  journal={Journal of the peripheral nervous system : JPNS},
  year={2008},
  volume={13 4},
  pages={267-74}
}
We investigated a series of bortezomib-treated patients and correlated the course of bortezomib-induced peripheral neurotoxicity with the presence or absence of peripheral neuropathy at baseline. Forty-eight patients were examined with the total neuropathy score reduced version (TNSr), visual analogue score (VAS) for pain, and nerve conduction studies at baseline and after two and four cycles of chemotherapy. Twenty-three patients had a baseline TNSr = 0-2, and 25 patients had a baseline TNSr… CONTINUE READING

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