Role of a heterologous retroviral transport element in the development of genetic complementation assay for mouse mammary tumor virus (MMTV) replication.

@article{Rizvi2009RoleOA,
  title={Role of a heterologous retroviral transport element in the development of genetic complementation assay for mouse mammary tumor virus (MMTV) replication.},
  author={Tahir A. Rizvi and Jahabar Ali and Pretty Susan Phillip and Akela A. Ghazawi and Preethi Jayanth and Farah Mustafa},
  journal={Virology},
  year={2009},
  volume={385 2},
  pages={464-72}
}
The mouse mammary tumor virus (MMTV) is a type B retrovirus that is unique from other retroviruses in having multiple "tissue specific" and "hormone inducible" promoters. This unique feature has lead to the increasing interest in studying the biology of MMTV replication with the ultimate goal of developing MMTV based vectors for potentially targeted human gene therapy. In this report, we describe, for the first time, the establishment of an in vivo genetic complementation assay to study various… CONTINUE READING
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