Role of a NK receptor, KLRE-1, in bone marrow allograft rejection: analysis with KLRE-1-deficient mice.

@article{Shimizu2004RoleOA,
  title={Role of a NK receptor, KLRE-1, in bone marrow allograft rejection: analysis with KLRE-1-deficient mice.},
  author={Eiko Shimizu and Junzo Koike and Hiroshi Wakao and Ken-ichiro Seino and Haruhiko Koseki and Terutaka Kakiuchi and Toshinori Nakayama and Masaru Taniguchi},
  journal={Blood},
  year={2004},
  volume={104 3},
  pages={
          781-3
        }
}
Natural killer (NK) cells play a pivotal role in the immune reaction during the bone marrow allograft rejection. Little is known, however, about the molecular mechanisms underlying the NK cell-mediated allograft recognition and rejection. In this report, we assessed the role of a recently identified NK receptor, killer cell lectinlike receptor 1 (KLRE-1), by generating knock-out mice. KLRE-1-deficient mice were born at an expected frequency and showed no aberrant phenotype on growth and… CONTINUE READING

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