Role of a Cdc42p effector pathway in recruitment of the yeast septins to the presumptive bud site.

@article{Iwase2006RoleOA,
  title={Role of a Cdc42p effector pathway in recruitment of the yeast septins to the presumptive bud site.},
  author={Masayuki Iwase and Jianying Luo and Satish Nagaraj and Mark S. Longtine and Hyong Bai Kim and Brian K. Haarer and Carlo Caruso and Zongtian Tong and John R. Pringle and Erfei Bi},
  journal={Molecular biology of the cell},
  year={2006},
  volume={17 3},
  pages={
          1110-25
        }
}
The septins are GTP-binding, filament-forming proteins that are involved in cytokinesis and other processes. In the yeast Saccharomyces cerevisiae, the septins are recruited to the presumptive bud site at the cell cortex, where they form a ring through which the bud emerges. We report here that in wild-type cells, the septins typically become detectable in the vicinity of the bud site several minutes before ring formation, but the ring itself is the first distinct structure that forms. Septin… CONTINUE READING