Role of Zinc Supplementation in Testicular and Epididymal Damages in Diabetic Rat: Involvement of Nrf2, SOD1, and GPX5

@article{Maremanda2016RoleOZ,
  title={Role of Zinc Supplementation in Testicular and Epididymal Damages in Diabetic Rat: Involvement of Nrf2, SOD1, and GPX5},
  author={Krishna Prahlad Maremanda and Sabbir Ahmed Khan and Gopabandhu B Jena},
  journal={Biological Trace Element Research},
  year={2016},
  volume={173},
  pages={452-464}
}
Zinc (Zn) is one of the most important trace elements required for several biological processes. Diabetes negatively affects many organs, and diabetic patients are often hypozincemic. The present study aims to investigate the role of Zn supplementation in the testes, epididymis, and sperms of streptozotocin (STZ)-induced diabetic rat. Serum, testicular, and sperm Zn contents were found to be altered in diabetic rat. Biochemical, histopathological, and protein expression profiles were determined… CONTINUE READING