Role of USF1 phosphorylation on cardiac alpha-myosin heavy chain promoter activity.

@article{Xiao2002RoleOU,
  title={Role of USF1 phosphorylation on cardiac alpha-myosin heavy chain promoter activity.},
  author={Qianxun Xiao and Agnes Kenessey and Kaie Ojamaa},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2002},
  volume={283 1},
  pages={H213-9}
}
Contractile activity of the cardiac myocyte is required for maintaining cell mass and phenotype, including expression of the cardiac-specific alpha-myosin heavy chain (alpha-MHC) gene. An E-box hemodynamic response element (HME) located at position -47 within the alpha-MHC promoter is both necessary and sufficient to confer contractile responsiveness to the… CONTINUE READING