Role of Transforming Growth Factor-β1 and Smads Signaling Pathway in Intrauterine Adhesion.

@article{Salma2016RoleOT,
  title={Role of Transforming Growth Factor-β1 and Smads Signaling Pathway in Intrauterine Adhesion.},
  author={Umme Salma and Min Xue and Md Sayed Ali Sheikh and Xiaoming Guan and Bin Xu and Aiqian Zhang and Lihua Huang and Da-bao Xu},
  journal={Mediators of inflammation},
  year={2016},
  volume={2016},
  pages={4158287}
}
The aim of the study was to evaluate the role of Smad3, Smad7, and TGF-β1 in intrauterine adhesion (IUA) patients and experimental rabbit models. 60 IUA patients, 30 control participants, and 18 female rabbits were enrolled in this study. We found that the plasma concentrations and protein expressions of TGF-β1 were significantly increased in patients and experimental rabbits compared to those in controls (P < 0.05). Furthermore, the mRNA and protein expression levels of Smad3 were… CONTINUE READING

From This Paper

Topics from this paper.
0 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…