Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury.

@article{Impellizzeri2015RoleOT,
  title={Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury.},
  author={Daniela Impellizzeri and Akbar Ahmad and Rosanna Di Paola and Michela Campolo and Michele Navarra and Emanuela Esposito and Salvatore Cuzzocrea},
  journal={Immunobiology},
  year={2015},
  volume={220 9},
  pages={1039-49}
}
Toll-like receptors (TLRs) are signaling receptors in the innate immune system that is specific immunologic response to systemic bacterial infection and injury. TLRs contribute to the initial induction of neuroinflammation in the CNS. In spinal cord injury (SCI) intricate immune cell interactions are triggered, typically consisting of a staggered… CONTINUE READING