Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination.

@article{Rostami2013RoleOT,
  title={Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination.},
  author={Abdolmohamad M. Rostami and Bogoljub Ciric},
  journal={Journal of the neurological sciences},
  year={2013},
  volume={333 1-2},
  pages={76-87}
}
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The etiology of MS is not well understood, but it is believed that myelin-specific CD4(+) T cells play a central role in initiating and orchestrating CNS inflammation. In this scenario, CD4(+) T cells, activated in the periphery, infiltrate the CNS, where, by secreting cytokines and chemokines, they start an inflammatory cascade. Given the central role of CD4(+) T cells in CNS autoimmunity, they have been… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…