Role of TRP channels in pain sensation.

  title={Role of TRP channels in pain sensation.},
  author={M F Chung and Sung Jun Jung and Seog Bae Oh},
  journal={Advances in experimental medicine and biology},
It is crucial for a living organism to recognize and discern potentially harmful noxious stimuli from innocuous stimuli to avoid hazards in the environment. However, unnecessary or exaggerated nociception is at best unpleasant and often compromises the quality of life. In order to lessen the intensity of nociception or eliminate the pathological pain, it is important to understand the nature of nociception and the mechanisms of hyperalgesia or allodynia. Transient receptor potential (TRP… CONTINUE READING