Role of TGF-β in melanoma.

@article{Busse2011RoleOT,
  title={Role of TGF-β in melanoma.},
  author={Antonia Busse and Ulrich Keilholz},
  journal={Current pharmaceutical biotechnology},
  year={2011},
  volume={12 12},
  pages={2165-75}
}
Human malignant melanoma is highly resistant to chemotherapy and current immunotherapeutic approaches induce long term remission only in the minority of patients. The transforming growth factor-β (TGF-β) has attracted much attention as a therapeutic target because it plays an important and pleiotropic role in melanoma progression. TGF-β is a multifunctional cytokine involved in the regulation of many cellular processes including cell proliferation, differentiation and survival. Resistance to… CONTINUE READING
Highly Cited
This paper has 138 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

139 Citations

020406080'13'15'17'19
Citations per Year
Semantic Scholar estimates that this publication has 139 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…