Role of T-type calcium current in identified D-hair mechanoreceptor neurons studied in vitro.

@article{Dubreuil2004RoleOT,
  title={Role of T-type calcium current in identified D-hair mechanoreceptor neurons studied in vitro.},
  author={Anne-Sophie Dubreuil and Hassan Boukhaddaoui and Gilles Desmadryl and Carlos Martinez-Salgado and Rabih Moshourab and Gary R Lewin and Patrick Carroll and Jean Valmier and Fr{\'e}d{\'e}rique Scamps},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2004},
  volume={24 39},
  pages={8480-4}
}
Different subsets of dorsal root ganglion (DRG) mechanoreceptors transduce low- and high-intensity mechanical stimuli. It was shown recently that, in vivo, neurotrophin-4 (NT-4)-dependent D-hair mechanoreceptors specifically express a voltage-activated T-type calcium channel (Ca(v)3.2) that may be required for their mechanoreceptive function. Here we show that D-hair mechanoreceptors can be identified in vitro by a rosette-like morphology in the presence of NT-4 and that these rosette neurons… CONTINUE READING