Role of T-type Ca2+ channels in the heart.

@article{Vassort2006RoleOT,
  title={Role of T-type Ca2+ channels in the heart.},
  author={Guy Vassort and Karel Talavera and Julio L. {\'A}lvarez},
  journal={Cell calcium},
  year={2006},
  volume={40 2},
  pages={205-20}
}
After the first demonstration 30 years ago that Ca2+ could permeate through two different channels, the occurrence and role of T-type Ca2+ current, ICaT have been the matter of hundreds of publications, including the two 1985' reports in various cardiac tissues and species. Except for its specific biophysical characteristics, ICaT is no longer so easily distinguished from the L-type Ca2+ current, ICaL, since it is also sensitive to multiple compounds and various neuromediators including the… CONTINUE READING