Role of T lymphocytes and interferon-gamma in ischemic stroke.

  title={Role of T lymphocytes and interferon-gamma in ischemic stroke.},
  author={Gokhan Yilmaz and Thiruma Valavan Arumugam and Karen Y. Stokes and Daniel Neil Granger},
  volume={113 17},
BACKGROUND Although lymphocyte recruitment and activation are associated with cerebral ischemia-reperfusion (I/R) injury, the contributions of specific lymphocyte subpopulations and lymphocyte-derived interferon-gamma (IFN-gamma) to stroke remain unknown. The objectives of this study were to define the contribution of specific populations of lymphocytes to the inflammatory and prothrombogenic responses elicited in the cerebral microvasculature by I/R and to investigate the role of T-cell… CONTINUE READING
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