Role of SpoVG in asymmetric septation in Bacillus subtilis.

  title={Role of SpoVG in asymmetric septation in Bacillus subtilis.},
  author={Kiyoshi Matsuno and Abraham L. Sonenshein},
  journal={Journal of bacteriology},
  volume={181 11},
Deletion of the citC gene, coding for isocitrate dehydrogenase, arrests sporulation of Bacillus subtilis at stage I after bipolar localization of the cell division protein FtsZ but before formation of the asymmetric septum. A spontaneous extragenic suppressor mutation that overcame the stage I block was found to map within the spoVG gene. The suppressing mutation and other spoVG loss-of-function mutations enabled citC mutant cells to form asymmetric septa and to activate the forespore-specific… CONTINUE READING


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