Role of Sox2 in the development of the mouse neocortex.

@article{BaniYaghoub2006RoleOS,
  title={Role of Sox2 in the development of the mouse neocortex.},
  author={Mahmud Bani-Yaghoub and Roger G. Tremblay and Joy X. Lei and Dongling Zhang and Bogdan Zurakowski and Jagdeep K Sandhu and Brandon Denis Smith and Maria Ribecco-Lutkiewicz and Jessica R. B. Kennedy and Paul R. Walker and Marianna Sikorska},
  journal={Developmental biology},
  year={2006},
  volume={295 1},
  pages={
          52-66
        }
}
The mammalian neocortex is established from neural stem and progenitor cells that utilize specific transcriptional and environmental factors to create functional neurons and astrocytes. Here, we examined the mechanism of Sox2 action during neocortical neurogenesis and gliogenesis. We established a robust Sox2 expression in neural stem and progenitor cells within the ventricular zone, which persisted until the cells exited the cell cycle. Overexpression of constitutively active Sox2 in neural… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 142 CITATIONS, ESTIMATED 55% COVERAGE

Neuroprotective Effects of GDNF-expressing Human Amniotic Fluid Cells

  • Stem Cell Reviews and Reports
  • 2013
VIEW 7 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

SOX2 overexpression affects neural differentiation of human pluripotent NT2/D1 cells

  • Biochemistry (Moscow)
  • 2014
VIEW 10 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Probing Stemness and Neural Commitment in Human Amniotic Fluid Cells

  • Stem Cell Reviews and Reports
  • 2010
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Epigenetic modifications of SOX2 enhancers, SRR1 and SRR2, correlate with in vitro neural differentiation.

  • Journal of neuroscience research
  • 2008
VIEW 10 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Astrocyte-Specific Deletion of Sox2 Promotes Functional Recovery After Traumatic Brain Injury.

  • Cerebral cortex
  • 2019
VIEW 6 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

The Effect of Traditional Chinese Medicine on Neural Stem Cell Proliferation and Differentiation

  • Aging and disease
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Functional characterization of the Japanese flounder (Paralichthys olivaceus) Sox2 gene promoter

  • Fish Physiology and Biochemistry
  • 2016
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2006
2019

CITATION STATISTICS

  • 12 Highly Influenced Citations

  • Averaged 6 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 90 REFERENCES

A tripotential glial precursor cell is present in the developing spinal cord.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Notch and neurogenesis.

  • Journal of neuroscience research
  • 1998
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL