Role of Sex Hormones in Development of Pituitary Adenoma

  title={Role of Sex Hormones in Development of Pituitary Adenoma},
  author={Vasilii N Babichev and Eugenia I Marova and Tatyana A. Kuznetsova and Elene I Adamskaya and Irina Shishkina and S. Yu. Kasumova},
  journal={Bulletin of Experimental Biology and Medicine},
Role of sex hormones in the development of pituitary adenomas was investigated by analyzing the content of nuclear estradiol and testosterone receptors in different tumors of the anterior pituitary: prolactinomas, meningiomas, growth hormone-producing adenomas, astrocytomas, neurinomas, and ependymomas. The concentration of nuclear estrogen and androgen receptors in prolactin-secreting pituitary adenomas was much higher than in growth hormone-producing adenomas and other pituitary tumors.