Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol.

@article{Gonzlez2010RoleOS,
  title={Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol.},
  author={Eva del R{\'i}o Gonz{\'a}lez and Maria Rosario Fern{\'a}ndez and Didac Marco and Eduard Calam and Lauro Sumoy and Xavier Par{\'e}s and Sylvie Dequin and Josep Antoni Biosca},
  journal={Applied and environmental microbiology},
  year={2010},
  volume={76 3},
  pages={
          670-9
        }
}
NAD-dependent butanediol dehydrogenase (Bdh1p) from Saccharomyces cerevisiae reversibly transforms acetoin to 2,3-butanediol in a stereospecific manner. Deletion of BDH1 resulted in an accumulation of acetoin and a diminution of 2,3-butanediol in two S. cerevisiae strains under two different growth conditions. The concentrations of (2R,3R)-2,3-butanediol are mostly dependent on Bdh1p activity, while those of (meso)-2,3-butanediol are also influenced by the activity of NADP(H)-dependent… CONTINUE READING
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