Role of SNAP-23 in trafficking of H+-ATPase in cultured inner medullary collecting duct cells.

  title={Role of SNAP-23 in trafficking of H+-ATPase in cultured inner medullary collecting duct cells.},
  author={Ayan Banerjee and G Li and Edward A. Alexander and John H. Schwartz},
  journal={American journal of physiology. Cell physiology},
  volume={280 4},
The trafficking of H+-ATPase vesicles to the apical membrane of inner medullary collecting duct (IMCD) cells utilizes a mechanism similar to that described in neurosecretory cells involving soluble N-ethylmaleimide-sensitive factor attachment protein target receptor (SNARE) proteins. Regulated exocytosis of these vesicles is associated with the formation of SNARE complexes. Clostridial neurotoxins that specifically cleave the target (t-) SNARE, syntaxin-1, or the vesicle SNARE, vesicle… 

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