Role of S100 Proteins in Colorectal Carcinogenesis

  title={Role of S100 Proteins in Colorectal Carcinogenesis},
  author={Paula Mor{\'a}vkov{\'a} and Darina Kohoutov{\'a} and Stanislav Rejchrt and Jiř{\'i} Cyrany and Jan Bure{\vs}},
  booktitle={Gastroenterology research and practice},
The family of S100 proteins represents 25 relatively small (9-13 kD) calcium binding proteins. These proteins possess a broad spectrum of important intracellular and extracellular functions. Colorectal cancer is the third most common cancer in men (after lung and prostate cancer) and the second most frequent cancer in women (after breast cancer) worldwide. S100 proteins are involved in the colorectal carcinogenesis through different mechanisms: they enable proliferation, invasion, and migration… CONTINUE READING
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